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GENE THERAPY

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Definition:
Gene delivery, the insertion of genes (e.g. via retroviral vectors) into selected cells in the body in order to:

- Cause those cells to produce specific therapeutic agents.

- Cause those cells to become (more) susceptible to a conventional therapeutic agent that previously was ineffective against that particular condition/disease.

- Cause those cells to become less susceptible to a conventional therapeutic agent.

- Counter the effects of abnormal (damaged) tumour suppressor genes via insertion of normal tumour suppressor genes.

- Cause expression of ribozymes that cleave oncogenes (cancer-causing genes).

- Introduce other therapeutics into cells.

Source Publication:
OECD, 2005, A Framework for Biotechnology Statistics, OECD, Paris, Annex 1: Glossary of Terms Used in the List-Based Definition.

Statistical Theme: Science and technology statistics

Created on Friday, July 01, 2005